Teratogens

Could there be some adverse reaction to the fetus due to exposure to a teratogen prior to conception and up to two weeks after conception? Can teratogens affect chromosome 3? Are they associated with CdLS?

Teratogens by definition in some way affect a fetus. In general, things that the mother is exposed to prior to conception and during the first two weeks after conception (when the embryo is traveling down to implant into the uterine wall) do not affect the fetus. Somehow there is protection until the embryo implants and starts using the mother’s blood supply. So, whatever this medication is, we can be reassuring. There are some medications that can affect fertility, but shouldn’t cause a condition like CdLS. Teratogens do not change genes and therefore have not been associated with CdLS.

TK 7-13-10

Legal Disclaimer:  Please take note that the CdLS Foundation’s Ask the Expert service is comprised of volunteer professionals in various areas of focus. Response times may vary and a response is not guaranteed. Answers are not considered a medical, behavioral, or educational consultation. Ask the Expert is not a substitute for the care and attention your child’s personal physician, psychologist, educational consultant, or social worker can deliver.