The CdLS Foundation has a vision and researchers have the determination to find treatments to help individuals with CdLS overcome many of the challenges they face.
CdLS is a genetic condition causing a range of medical, developmental and physical challenges, including:
- Gastroesophageal reflux
- Craniofacial defects
- Heart defects
- Self-injurious behavior
- Communications issues (e.g., selective mutism, non-verbal, etc.)
- Developmental delays and intellectual disability
- Behavioral problems and autism
- Feeding problems
CdLS is a cohesinopathy caused by mutations in any one of the following genes: NIPBL, SMC1A, SMC3, HDAC8, RAD21, BRD4 and ANKRD11. Only 70 percent of individuals tested to date have a change in any of the mentioned genes, with the majority having an NIPBL mutation.
The next grant cycle begins January 15, 2019
Letters of Intent deadline: February 28, 2019*
Application deadline: March 30, 2019
Award notification: May 31, 2019
Grant checks mailed: Fall of 2019*
*Once a Letter of Intent has been submitted, proceed with the remainder of the grant application. The purpose of the Letter of Intent is to help the Research Committee to obtain the appropriate reviewers for your grant application.