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CdLS Research Grants

CdLS Research Grants

The CdLS Foundation has a vision and researchers have the determination to find treatments to help individuals with CdLS overcome many of the challenges they face.

The Cornelia de Lange Syndrome (CdLS) Foundation announces the availability of funding for basic science and clinical research in 2015. Letters of intent and applications are accepted beginning January 15, 2015.

Background
CdLS is genetic condition causing a range of medical, developmental and physical challenges, including:

  • Gastroesophageal reflux
  • Craniofacial defects
  • Heart defects
  • Seizures
  • Immunodeficiency
  • Self-injurious behavior
  • Communications issues (e.g., selective mutism, non-verbal, etc.)
  • Developmental delays and intellectual disability
  • Behavioral problems and autism
  • Feeding problems

CdLS is a cohesinopathy caused by mutations in any one of the following genes: NIPBL, SMC1A, SMC3, HDAC8 and RAD21. Only 70 percent of individuals tested to date have a change in any of the mentioned genes, with the majority having an NIPBL mutation.

Timeline
Letters of Intent deadline: April 15, 2015
Application deadline: May 15, 2015
Award notification: July 15, 2015
Grant checks mailed: September 1, 2015

View the guidelines
Download the application

Funding is available annually. The next grant cycle begins in early 2015.

The Foundation has previously approved grants for the following projects:

For questions,